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DNA strand breaks produced by oxidative stress in mammalian cells exhibit 3'-phosphoglycolate termini.

In recent years two mechanisms have been proposed for the production of DNA strand breaks in cells undergoing oxidative stress: (i) DNA attack by OH radical, produced by Fenton reaction catalyzed by DNA-bound iron; and (ii) DNA attack by calcium-activated nucleases, due to the increase of cytosolic...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Bertoncini, C R, Meneghini, R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1995
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7659523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.15.2995
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