A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms

Electron microscopy (EM) achieves the highest spatial resolution in protein localization, but specific protein EM labeling has lacked generally applicable genetically encoded tags for in situ visualization in cells and tissues. Here we introduce “miniSOG” (for mini Singlet Oxygen Generator), a fluor...

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Detalhes bibliográficos
Main Authors: Shu, Xiaokun, Lev-Ram, Varda, Deerinck, Thomas J., Qi, Yingchuan, Ramko, Ericka B., Davidson, Michael W., Jin, Yishi, Ellisman, Mark H., Tsien, Roger Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071375/
https://ncbi.nlm.nih.gov/pubmed/21483721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001041
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