A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms

Electron microscopy (EM) achieves the highest spatial resolution in protein localization, but specific protein EM labeling has lacked generally applicable genetically encoded tags for in situ visualization in cells and tissues. Here we introduce “miniSOG” (for mini Singlet Oxygen Generator), a fluor...

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Main Authors: Shu, Xiaokun, Lev-Ram, Varda, Deerinck, Thomas J., Qi, Yingchuan, Ramko, Ericka B., Davidson, Michael W., Jin, Yishi, Ellisman, Mark H., Tsien, Roger Y.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071375/
https://ncbi.nlm.nih.gov/pubmed/21483721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001041
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