A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms

Electron microscopy (EM) achieves the highest spatial resolution in protein localization, but specific protein EM labeling has lacked generally applicable genetically encoded tags for in situ visualization in cells and tissues. Here we introduce “miniSOG” (for mini Singlet Oxygen Generator), a fluor...

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Main Authors: Shu, Xiaokun, Lev-Ram, Varda, Deerinck, Thomas J., Qi, Yingchuan, Ramko, Ericka B., Davidson, Michael W., Jin, Yishi, Ellisman, Mark H., Tsien, Roger Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071375/
https://ncbi.nlm.nih.gov/pubmed/21483721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001041
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