Tuberculin-Specific T Cells Are Reduced in Active Pulmonary Tuberculosis Compared to LTBI or Status Post BCG Vaccination

Functional characteristics of tuberculosis (TB)–specific CD4 T cells were studied in clinically active pulmonary TB (n = 21) and high TB exposure including LTBI (n = 17). Following tuberculin stimulation, activated CD4 T cells were identified by flow-cytometry (CD154 up-regulation, degranulation, in...

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Библиографические подробности
Главные авторы: Streitz, Mathias, Fuhrmann, Stephan, Powell, Fiona, Quassem, Ali, Nomura, Laurel, Maecker, Holden, Martus, Peter, Volk, Hans-Dieter, Kern, Florian
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071115/
https://ncbi.nlm.nih.gov/pubmed/21186260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq065
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