Targeted Delivery of Small Interfering RNA Using Reconstituted High-Density Lipoprotein Nanoparticles

RNA interference holds tremendous potential as a therapeutic approach, especially in the treatment of malignant tumors. However, efficient and biocompatible delivery methods are needed for systemic delivery of small interfering RNA (siRNA). To maintain a high level of growth, tumor cells scavenge hi...

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Autores principales: Shahzad, Mian MK, Mangala, Lingegowda S, Han, Hee Dong, Lu, Chunhua, Bottsford-Miller, Justin, Nishimura, Masato, Mora, Edna M, Lee, Jeong-Won, Stone, Rebecca L, Pecot, Chad V, Thanapprapasr, Duangmani, Roh, Ju-Won, Gaur, Puja, Nair, Maya P, Park, Yun-Yong, Sabnis, Nirupama, Deavers, Michael T, Lee, Ju-Seog, Ellis, Lee M, Lopez-Berestein, Gabriel, McConathy, Walter J, Prokai, Laszlo, Lacko, Andras G, Sood, Anil K
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071079/
https://ncbi.nlm.nih.gov/pubmed/21472135
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