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Deep Sequencing Reveals Mixed Infection with 2009 Pandemic Influenza A (H1N1) Virus Strains and the Emergence of Oseltamivir Resistance

Mixed infections with seasonal influenza A virus strains are a common occurrence and an important source of genetic diversity. Prolonged viral shedding, as observed in immunocompromised individuals, can lead to mutational accumulation over extended periods. Recently, drug resistance was reported in...

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Hlavní autoři: Ghedin, Elodie, Laplante, Jennifer, DePasse, Jay, Wentworth, David E., Santos, Roberto P., Lepow, Martha L., Porter, Joanne, Stellrecht, Kathleen, Lin, Xudong, Operario, Darwin, Griesemer, Sara, Fitch, Adam, Halpin, Rebecca A., Stockwell, Timothy B., Spiro, David J., Holmes, Edward C., George, Kirsten St.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071067/
https://ncbi.nlm.nih.gov/pubmed/21288815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq040
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