Presence of Oseltamivir-Resistant Pandemic A/H1N1 Minor Variants Before Drug Therapy With Subsequent Selection and Transmission

A small proportion (1%–1.5%) of 2009 pandemic influenza A/H1N1 virus strains (A[H1N1]pdm09) are oseltamivir resistant, almost exclusively because of a H275Y mutation in the neuraminidase protein. However, many individuals infected with resistant strains had not received antivirals. Whether drug-resi...

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Dades bibliogràfiques
Autors principals: Ghedin, Elodie, Holmes, Edward C., DePasse, Jay V., Pinilla, Lady Tatiana, Fitch, Adam, Hamelin, Marie-Eve, Papenburg, Jesse, Boivin, Guy
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475640/
https://ncbi.nlm.nih.gov/pubmed/22966122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis571
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