Immuno-epidemiologic Correlates of Pandemic H1N1 Surveillance Observations: Higher Antibody and Lower Cell-Mediated Immune Responses with Advanced Age

Background. Pandemic H1N1 (pH1N1) surveillance data showed lower attack rates but higher risk of severe outcomes with advanced age. We explored immuno-epidemiologic correlates of surveillance findings including humoral and cell-mediated immunity (CMI). Methods. In an age-based design, ∼100 banked/re...

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Bibliografiske detaljer
Main Authors: Skowronski, Danuta M., Hottes, Travis S., McElhaney, Janet E., Janjua, Naveed Z., Sabaiduc, Suzana, Chan, Tracy, Gentleman, Beth, Purych, Dale, Gardy, Jennifer, Patrick, David M., Brunham, Robert C., De Serres, Gaston, Petric, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071066/
https://ncbi.nlm.nih.gov/pubmed/21288814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq039
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