Immuno-epidemiologic Correlates of Pandemic H1N1 Surveillance Observations: Higher Antibody and Lower Cell-Mediated Immune Responses with Advanced Age

Background. Pandemic H1N1 (pH1N1) surveillance data showed lower attack rates but higher risk of severe outcomes with advanced age. We explored immuno-epidemiologic correlates of surveillance findings including humoral and cell-mediated immunity (CMI). Methods. In an age-based design, ∼100 banked/re...

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Detalhes bibliográficos
Main Authors: Skowronski, Danuta M., Hottes, Travis S., McElhaney, Janet E., Janjua, Naveed Z., Sabaiduc, Suzana, Chan, Tracy, Gentleman, Beth, Purych, Dale, Gardy, Jennifer, Patrick, David M., Brunham, Robert C., De Serres, Gaston, Petric, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071066/
https://ncbi.nlm.nih.gov/pubmed/21288814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq039
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