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Non-canonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio
The receptor Notch interacts with the Abl tyrosine kinase signaling pathway to control axon growth and guidance in Drosophila motor neurons. In part, this is mediated by binding to Trio, a guanine nucleotide exchange factor (GEF) for Rho GTPases. We show here that one of the two GEF domains of Trio,...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070923/ https://ncbi.nlm.nih.gov/pubmed/21246649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22525 |
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