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The Efficacy of Radiotherapy Relies Upon Induction of Type I Interferon-Dependent Innate and Adaptive Immunity

The most widely held explanation for the efficacy of local radiotherapy (RT) is based on direct cytotoxicity to cancer cells through the induction of lethal DNA damage. Recent studies have demonstrated that local ablative radiation of established tumors can lead to increased T cell priming and T cel...

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Autors principals: Burnette, Byron, Liang, Hua, Lee, Youjin, Chlewicki, Lukasz, Khodarev, Nikolai N., Weichselbaum, Ralph R., Fu, Yang-Xin, Auh, Sogyong L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070872/
https://ncbi.nlm.nih.gov/pubmed/21300764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2820
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