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Structure-based Systems Biology for Analyzing Off-target Binding
Here off-target binding implies the binding of a small molecule of therapeutic interest to a protein target other than the primary target for which it was intended. Increasingly such off-targeting appears to be the norm rather than the exception, rational drug design notwithstanding, and can lead to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070778/ https://ncbi.nlm.nih.gov/pubmed/21292475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.01.004 |
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