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Reverse transcriptase and substrate dependence of the RNA hypermutagenesis reaction.

G-->A hypermutation is a remarkable phenomenon resulting from retroviral reverse transcription in the presence of highly biased dNTP concentrations. Of the three reverse transcriptases (RTases) available, those of human immunodeficiency virus type 1 (HIV-1), avian myeloblastosis virus (AMV) and M...

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Bibliographic Details
Main Authors: Martínez, M A, Sala, M, Vartanian, J P, Wain-Hobson, S
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307076/
https://ncbi.nlm.nih.gov/pubmed/7544458
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