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The Utilization of Pathogen-Like Cellular Trafficking by Single Chain Block Copolymer

Amphiphilic triblock copolymer, poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), Pluronic(®) P85, is unexpectedly shown to utilize sophisticated cellular trafficking mechanisms and enter brain microvessel endothelial cells and primary neurons that are poorly penetrable. Though ca...

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Bibliographic Details
Main Authors: Sahay, Gaurav, Gautam, Vivek, Luxenhofer, Robert, Kabanov, Alexander V
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070746/
https://ncbi.nlm.nih.gov/pubmed/19963266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.11.020
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