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Positive Allosteric Modulators of Type 5 Metabotropic Glutamate Receptors (mGluR5) and Their Therapeutic Potential for the Treatment of CNS Disorders

Studies utilizing selective pharmacological antagonists or targeted gene deletion have demonstrated that type 5 metabotropic glutamate receptors (mGluR5) are critical mediators and potential therapeutic targets for the treatment of numerous disorders of the central nervous system (CNS), including de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cleva, Richard M., Olive, M. Foster
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070661/
https://ncbi.nlm.nih.gov/pubmed/21368721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16032097
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