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Circulating herpes simplex type 1 (HSV-1)-specific CD8(+ )T cells do not access HSV-1 latently infected trigeminal ganglia

BACKGROUND: Therapeutic vaccines can be designed to enhance existing T cell memory populations for increased protection against re-infection. In the case of herpes simplex virus type 1, recurrent disease results from reactivation of latent virus in sensory ganglia, which is controlled in part by a g...

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Main Authors: Himmelein, Susanne, St Leger, Anthony J, Knickelbein, Jared E, Rowe, Alexander, Freeman, Michael L, Hendricks, Robert L
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070622/
https://ncbi.nlm.nih.gov/pubmed/21429183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-4280-2-5
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