The Cdc42 Guanine Nucleotide Exchange Factor FGD1 Regulates Osteogenesis in Human Mesenchymal Stem Cells

Loss of function mutations in FGD1 result in faciogenital dysplasia, an X-linked human developmental disorder that adversely affects the formation of multiple skeletal structures. FGD1 encodes a guanine nucleotide exchange factor that specifically activates Cdc42, a Rho family small GTPase that regu...

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Main Authors: Gao, Lin, Gorski, Jerome L., Chen, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2011
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070587/
https://ncbi.nlm.nih.gov/pubmed/21356349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.051
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