Colorectal Cancer Cells Activate Adjacent Fibroblasts Resulting in FGF1/FGFR3 Signaling and Increased Invasion

Cancer-associated fibroblasts expressing fibroblast activation protein (FAP) have been implicated in the invasive behavior of colorectal cancer. In this study, we use FAP expression as a marker of fibroblast activation and analyze the effect of activated fibroblasts on colorectal cancer migration an...

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Main Authors: Henriksson, Maria L., Edin, Sofia, Dahlin, Anna M., Oldenborg, Per-Arne, Öberg, Åke, Van Guelpen, Bethany, Rutegård, Jörgen, Stenling, Roger, Palmqvist, Richard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070577/
https://ncbi.nlm.nih.gov/pubmed/21356388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.008
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