Mitochondrial Apoptosis-Induced Channel (MAC) Function Triggers a Bax/Bak-Dependent Bystander Effect

Collateral spread of apoptosis to nearby cells is referred to as the bystander effect, a process that is integral to tissue homeostasis and a challenge to anticancer therapies. In many systems, apoptosis relies on permeabilization of the mitochondrial outer membrane to factors such as cytochrome c a...

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Главные авторы: Peixoto, Pablo M., Lue, Jennifer K., Ryu, Shin-Young, Wroble, Brian N., Sible, Jill C., Kinnally, Kathleen W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2011
Предметы:
Short Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070563/
https://ncbi.nlm.nih.gov/pubmed/21224042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.014
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