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Functional Relevance of CpG Island Length for Regulation of Gene Expression

CpG islands mark CpG-enriched regions in otherwise CpG-depleted vertebrate genomes. While the regulatory importance of CpG islands is widely accepted, it is little appreciated that CpG islands vary greatly in lengths. For example, CpG islands in the human genome vary ∼30-fold in their lengths. Here...

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Detalhes bibliográficos
Main Authors: Elango, Navin, Yi, Soojin V.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070517/
https://ncbi.nlm.nih.gov/pubmed/21288871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.126094
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