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Use of oligonucleotides to define the site of interstrand cross-links induced by Adriamycin.

It has been known for several years that Adriamycin forms adducts and interstrand cross-links when reacted for long periods of time with bacterial and mammalian DNA in vitro, with the cross-link being restricted to 2 bp elements containing GpC sequences. The self-complementary 20mer deoxyoligonucleo...

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Publicat a:Nucleic Acids Res
Autors principals: Cutts, S M, Phillips, D R
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1995
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7630722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.13.2450
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