RNAi mediated silencing of Nrf2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy

Nuclear factor erythroid-2 related factor-2 (Nrf2) is a redox-sensitive transcription factor that regulates the expression of electrophile and xenobiotic detoxification enzymes and efflux proteins, which confer cytoprotection against oxidative stress and apoptosis in normal cells. Loss of function m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Singh, Anju, Boldin-Adamsky, Swetlana, Thimmulappa, Rajesh K, Rath, Srikanta K, Ashush, Hagit, Coulter, Jonathan, Blackford, Amanda, Goodman, Steven N, Bunz, Fred, Watson, Walter H, Gabrielson, Edward, Feinstein, Elena, Biswal, Shyam
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070411/
https://ncbi.nlm.nih.gov/pubmed/18829555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1401
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