Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relation with the clinical inefficiency of transplatin.

The reaction between trans-diamminedichloroplatinum(II) and single-stranded oligonucleotides containing the sequence d(GXG) (X being an adenine, cytosine or thymine residue) yields trans-[Pt(NH3)2[(GXG)-GN7,GN7]] intrastrand cross-links. These cross-links do not prevent the pairing of the platinated...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Boudvillain, M, Dalbiès, R, Aussourd, C, Leng, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1995
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7630715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.13.2381
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