Clinical Evidence for Predominance of Delta-5 Steroid Production in Women with Polycystic Ovary Syndrome

CONTEXT: In women with polycystic ovary syndrome (PCOS), the basis for ovarian androgen overproduction involves an overall increase of steroidogenesis, notably in the delta-4 pathway. However, in vitro studies have suggested that excessive androgen production occurs predominantly through the delta-5...

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Hoofdauteurs: Rosencrantz, Marcus A., Coffler, Mickey S., Haggan, Annette, Duke, Kimberly B., Donohue, Michael C., Shayya, Rana F., Su, H. Irene, Chang, R. Jeffrey
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2011
Onderwerpen:
Endocrine Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070255/
https://ncbi.nlm.nih.gov/pubmed/21270326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2200
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