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Predicted structures and dynamics for agonists and antagonists bound to serotonin 5-HT2B and 5-HT2C receptors

Subtype 2 Serotonin (5-Hydroxytryptamine, 5-HT) receptors are major drug targets for schizophrenia, feeding disorders, perception, depression, migraines, hypertension, anxiety, hallucinogens, and gastrointestinal dysfunctions.(1) We report here the predicted structure of 5-HT2B and 5-HT2C receptor b...

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Autors principals: Kim, Soo-Kyung, Li, Youyong, Abrol, Ravinder, Heo, Jiyoung, Goddard, William A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070210/
https://ncbi.nlm.nih.gov/pubmed/21299232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci100375b
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