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Ribozyme-mediated RNA degradation in nuclei suspension.

Ribozymes containing 2'-fluoro- and 2'-amino-modified pyrimidine nucleosides in combination with terminal phosphorothioate linkages were targeted against HTLV-I tax RNA. In order to examine the activity of such chemically modified ribozymes in the nuclear environment, they were incubated w...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Heidenreich, O, Kang, S H, Brown, D A, Xu, X, Swiderski, P, Rossi, J J, Eckstein, F, Nerenberg, M
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1995
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7610051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.12.2223
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