Chemokine Expression From Oncolytic Vaccinia Virus Enhances Vaccine Therapies of Cancer

Tumor vaccines can induce robust immune responses targeting tumor antigens in the clinic, but antitumor effects have been disappointing. One reason for this is ineffective tumor infiltration of the cytotoxic T lymphocytes (CTLs) produced. Oncolytic viruses are capable of selectively replicating with...

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Bibliografiske detaljer
Main Authors: Li, Jun, O'Malley, Mark, Urban, Julie, Sampath, Padma, Guo, Z Sheng, Kalinski, Pawel, Thorne, Steve H, Bartlett, David L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070102/
https://ncbi.nlm.nih.gov/pubmed/21266959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.312
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