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Chemokine Expression From Oncolytic Vaccinia Virus Enhances Vaccine Therapies of Cancer

Tumor vaccines can induce robust immune responses targeting tumor antigens in the clinic, but antitumor effects have been disappointing. One reason for this is ineffective tumor infiltration of the cytotoxic T lymphocytes (CTLs) produced. Oncolytic viruses are capable of selectively replicating with...

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Detalhes bibliográficos
Main Authors: Li, Jun, O'Malley, Mark, Urban, Julie, Sampath, Padma, Guo, Z Sheng, Kalinski, Pawel, Thorne, Steve H, Bartlett, David L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070102/
https://ncbi.nlm.nih.gov/pubmed/21266959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.312
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