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Triple helix DNA alters nucleosomal histone-DNA interactions and acts as a nucleosome barrier.

Oligonucleotides which form triple helical complexes on double-stranded DNA have been previously reported to selectively inhibit transcription both in vitro and in vivo by physically blocking RNA polymerase or transcription factor access to the DNA template. Here we show that a 16mer oligonucleotide...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Westin, L, Blomquist, P, Milligan, J F, Wrange, O
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 1995
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7610046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.12.2184
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