Triple helix DNA alters nucleosomal histone-DNA interactions and acts as a nucleosome barrier.
Oligonucleotides which form triple helical complexes on double-stranded DNA have been previously reported to selectively inhibit transcription both in vitro and in vivo by physically blocking RNA polymerase or transcription factor access to the DNA template. Here we show that a 16mer oligonucleotide...
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| Опубліковано в:: | Nucleic Acids Res |
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| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Oxford University Press
1995
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| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7610046/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.12.2184 |
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