Single point mutations affect fatty acid block of human myocardial sodium channel α subunit Na(+) channels
Suppression of cardiac voltage-gated Na(+) currents is probably one of the important factors for the cardioprotective effects of the n-3 polyunsaturated fatty acids (PUFAs) against lethal arrhythmias. The α subunit of the human cardiac Na(+) channel (hH1(α)) and its mutants were expressed in human e...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061003798 |
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