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A Mouse Model of β-Thalassemia Shows a Liver-Specific Down-Regulation of Abcc6 Expression
β-Thalassemia and pseudoxanthoma elasticum (PXE) are distinct genetic disorders. Yet, a dystrophic mineralization phenotype similar to PXE has frequently been associated with β-thalassemia or sickle cell anemia patients of Mediterranean descent. These calcifications are clinically and structurally i...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069908/ https://ncbi.nlm.nih.gov/pubmed/21281810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.004 |
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