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Co-Occurrence of Types 1 and 2 PrP(res) in Sporadic Creutzfeldt-Jakob Disease MM1

The genotype (M/M, M/V, or V/V) at polymorphic codon 129 of the human prion protein (PrP) gene and the type (1 or 2) of protease-resistant PrP (PrP(res)) in the brain are major determinants of the clinicopathological phenotypes of sporadic Creutzfeldt-Jakob disease (sCJD). According to this molecula...

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Autori principali: Kobayashi, Atsushi, Mizukoshi, Kenta, Iwasaki, Yasushi, Miyata, Hajime, Yoshida, Yasuji, Kitamoto, Tetsuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069892/
https://ncbi.nlm.nih.gov/pubmed/21356381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.069
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