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Direct Alkylation of Heteroaryls using Potassium Alkyl- and Alkoxymethyltrifluoroborates

[Image: see text] A direct alkylation of various heteroaryls using stoichiometric potassium alkyl and alkoxymethyltrifluoroborates has been developed. This method leads to the synthesis of complex substituted heterocycles, which have been obtained with yields up to 89%.

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Detalhes bibliográficos
Main Authors: Molander, Gary A., Colombel, Virginie, Braz, Valerie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069859/
https://ncbi.nlm.nih.gov/pubmed/21391555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2003572
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