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Direct Alkylation of Heteroaryls using Potassium Alkyl- and Alkoxymethyltrifluoroborates

[Image: see text] A direct alkylation of various heteroaryls using stoichiometric potassium alkyl and alkoxymethyltrifluoroborates has been developed. This method leads to the synthesis of complex substituted heterocycles, which have been obtained with yields up to 89%.

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Molander, Gary A., Colombel, Virginie, Braz, Valerie A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069859/
https://ncbi.nlm.nih.gov/pubmed/21391555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2003572
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