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Nucleophosmin (NPM1) Mutations in Adult and Childhood Acute Myeloid Leukemia: Towards Definition of a New Leukemia Entity
Nucleophosmin (NPM) is a ubiquitously expressed chaperone protein that shuttles rapidly between the nucleous and cytoplasm, but predominantly resides in the nucleous. It plays key roles in ribosome biogenesis, centrosome duplication, genomic stability, cell cycle progression and apoptosis. Somatic m...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069851/ https://ncbi.nlm.nih.gov/pubmed/19569254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hon.904 |
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