RhoB Loss Prevents Streptozotocin-Induced Diabetes and Ameliorates Diabetic Complications in Mice

RhoB is an early-response gene whose expression is elevated by multiple cellular stresses; this gene plays an important role in cancer, macrophage motility, and apoptosis. These factors are essential for the onset of type 1 diabetes mellitus and related complications. This study explores the role of...

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Main Authors: Bravo-Nuevo, Arturo, Sugimoto, Hikaru, Iyer, Seema, Fallon, Zachary, Lucas, Jason M., Kazerounian, Shiva, Prendergast, George C., Kalluri, Raghu, Shapiro, Nathan I., Benjamin, Laura E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069827/
https://ncbi.nlm.nih.gov/pubmed/21224061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.040
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