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Good COP1 or bad COP1? In vivo veritas

The evolutionarily conserved protein COP1 has been shown to operate as an E3 ubiquitin ligase complex, and a number of putative substrates have been identified, including the c-JUN oncoprotein and p53 tumor suppressor protein. New work by Migliorini and colleagues described in the current issue of J...

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Bibliografiske detaljer
Main Authors: Wei, Wenyi, Kaelin, William G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069793/
https://ncbi.nlm.nih.gov/pubmed/21403396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57080
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