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IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function
Wiskott-Aldrich syndrome (WAS) is a primary immunodeficiency associated with an increased susceptibility to herpesvirus infection and hematologic malignancy as well as a deficiency of NK cell function. It is caused by defective WAS protein (WASp). WASp facilitates filamentous actin (F-actin) branchi...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069781/ https://ncbi.nlm.nih.gov/pubmed/21383498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44862 |
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