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MDM2 REGULATES ESTROGEN RECEPTOR α AND ESTROGEN-RESPONSIVENESS IN BREAST CANCER CELLS
Mdm2 is a multifunctional protein that modulates nuclear receptor-mediated transactivation. In this study, we show that Mdm2 significantly enhanced estrogen receptor α (ERα) and ERα/specificity protein (Sp)-mediated transactivation in MCF-7 and ZR-75 breast cancer cells. This was demonstrated by bot...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069690/ https://ncbi.nlm.nih.gov/pubmed/21169420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-10-0110 |
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