Overcoming potassium-mediated triplex inhibition.
Sequence-specific duplex DNA recognition by oligonucleotide-directed triple helix formation is a possible approach to in vivo gene inhibition. However, triple helix formation involving guanine-rich oligonucleotides is inhibited by physiological ions, particularly K+, most likely due to oligonucleoti...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
1995
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| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7596821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.11.1936 |
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