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Overcoming potassium-mediated triplex inhibition.
Sequence-specific duplex DNA recognition by oligonucleotide-directed triple helix formation is a possible approach to in vivo gene inhibition. However, triple helix formation involving guanine-rich oligonucleotides is inhibited by physiological ions, particularly K+, most likely due to oligonucleoti...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1995
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306966/ https://ncbi.nlm.nih.gov/pubmed/7596821 |
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