Llwytho...

Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct ligated rats and human hepatic cells

Cholestasis leads to liver cell death, fibrosis, cirrhosis, and eventually liver failure. Despite limited benefits, ursodeoxycholic acid (UDCA) is the only FDA approved treatment for cholestatic disorders. Retinoic acid (RA) is a ligand for nuclear receptors, which modulate bile salt homeostasis. RA...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: He, Hongwei, Mennone, Albert, Boyer, James L., Cai, Shi-Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069505/
https://ncbi.nlm.nih.gov/pubmed/21274875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24047
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