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Consequences of the overexpression of a eukaryotic membrane protein, the human KDEL receptor, in Escherichia coli

Escherichia coli is the most widely used host for producing membrane proteins. Thus far, to study the consequences of membrane protein overexpression in E. coli we have focussed on prokaryotic membrane proteins as overexpression targets. Their overexpression results in the saturation of the Sec-tran...

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Bibliografiske detaljer
Main Authors: Klepsch, Mirjam M., Persson, Jan O., de Gier, Jan-Willem L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069486/
https://ncbi.nlm.nih.gov/pubmed/21316372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.007
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