VentX trans-Activates p53 and p16(ink4a) to Regulate Cellular Senescence

Cell senescence is a process of irreversible arrest of cell proliferation and plays an important role in tumor suppression. Recent studies showed that Wnt inhibition is a trigger of cellular senescence. Using methods of reverse genetics, we recently identified VentX, a human homolog of the vertebrat...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Xiaoming, Gao, Hong, Ke, Weixiong, Hager, Martin, Xiao, Sheng, Freeman, Michael R., Zhu, Zhenglun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069469/
https://ncbi.nlm.nih.gov/pubmed/21325273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.206078
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