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VentX trans-Activates p53 and p16(ink4a) to Regulate Cellular Senescence
Cell senescence is a process of irreversible arrest of cell proliferation and plays an important role in tumor suppression. Recent studies showed that Wnt inhibition is a trigger of cellular senescence. Using methods of reverse genetics, we recently identified VentX, a human homolog of the vertebrat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069469/ https://ncbi.nlm.nih.gov/pubmed/21325273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.206078 |
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