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Amino Acid Signaling in Yeast: Activation of Ssy5 Protease Is Associated with Its Phosphorylation-induced Ubiquitylation

The yeast Ssy5 protein is a serine-type endoprotease autoprocessed into a catalytic domain and a large inhibitory prodomain. When external amino acids are detected by the plasma membrane Ssy1 sensor, Ssy5 is activated and catalyzes endoproteolytic processing of the Stp1 and Stp2 transcription factor...

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Detalhes bibliográficos
Main Authors: Abdel-Sater, Fadi, Jean, Cathy, Merhi, Ahmad, Vissers, Stéphan, André, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069403/
https://ncbi.nlm.nih.gov/pubmed/21310956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200592
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