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Function of the upstream hypersensitive sites of the chicken beta-globin gene cluster in mice.

We have shown previously that the chicken beta A-globin gene, with its 3' enhancer, is expressed in a copy number-dependent manner in transgenic mice. The expression level was low but increased approximately 6-fold upon inclusion of 11 kb of upstream DNA containing four DNase I hypersensitive s...

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Hlavní autoři: Reitman, M, Lee, E, Westphal, H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC306937/
https://ncbi.nlm.nih.gov/pubmed/7784184
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