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Mechanical regulation of cell function with geometrically modulated elastomeric substrates

We report the establishment of a library of micromolded elastomeric micropost arrays to modulate substrate rigidity independently of effects on adhesive and other material surface properties. We demonstrate that micropost rigidity impacts cell morphology, focal adhesions, cytoskeletal contractility,...

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Autori principali: Fu, Jianping, Wang, Yang-Kao, Yang, Michael T., Desai, Ravi A., Yu, Xiang, Liu, Zhijun, Chen, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069358/
https://ncbi.nlm.nih.gov/pubmed/20676108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1487
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