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Mechanical regulation of cell function with geometrically modulated elastomeric substrates
We report the establishment of a library of micromolded elastomeric micropost arrays to modulate substrate rigidity independently of effects on adhesive and other material surface properties. We demonstrate that micropost rigidity impacts cell morphology, focal adhesions, cytoskeletal contractility,...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069358/ https://ncbi.nlm.nih.gov/pubmed/20676108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1487 |
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