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Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy

Zebrafish were proposed as an alternative to mammalian models to assess the efficacy and toxicity of antileukemic drugs. Due to the limited number of transgenic zebrafish leukemia models, we explored human leukemic cell xenograft in zebrafish embryos. Human leukemic cell lines and blast cells sorted...

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Detalhes bibliográficos
Main Authors: Pruvot, Benoist, Jacquel, Arnaud, Droin, Nathalie, Auberger, Patrick, Bouscary, Didier, Tamburini, Jérome, Muller, Marc, Fontenay, Michaela, Chluba, Johanna, Solary, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069240/
https://ncbi.nlm.nih.gov/pubmed/21228037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.031401
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